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ThebaineA minor constituent of opium, thebaine is chemically similar to both morphine and codeine, but produces stimulatory rather than depressant effects. Thebaine is not used therapeutically, but is converted into a variety of compounds including codeine, hydrocodone, oxycodone, oxymorphone, nalbuphine, naloxone, naltrexone, and buprenorphine. It is controlled in Schedule II of the Controlled Substances Act as well as under international law.
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