1499Centuries: 14th century - 15th century - 16th century
- July 22 - Battle of Dornach - The Swiss decisively defeat the Imperial army of Emperor Maximilian I.
- July 28 - First Battle of Lepanto - The Turkish navy wins a decisive victory over the Venetians.
- September 22 - Treaty of Basel. Maximilian is forced to grant the Swiss de facto independence.
- The French under Louis XII seize Milan, driving out Duke Ludovico Sforza